What Is Myostatin
- Is a Gene (Protein)
- Messes up satellite cell activation
- Messes up protein synthesis
- Messes up insulin sensitivity
- increases protein breakdown (muscle loss)
- prevents Hyperplasia
- The 3 gram rule (If your body synthesizes 3 grams of protein everyday, you’ll gain 1 pound of muscle a month)
Examples Of Low Myostatin
![](/wp-content/uploads/2023/05/bull.jpg)
![](/wp-content/uploads/2023/05/kid.jpg)
High Levels Of Myostatin
- Women (Women have up to twice as many myostatin receptors as Men)
- Old People (Myostatin levels drop with age)
- South Asian (South Asians are genetically predisposed to have higher levels of myostatin, which is why they are usually lean)
- Bed Ridden, Casts, Wheelchairs
10 Fastest Ways To Lower Myostatin
Follistatin
- Gene (Protein)
- No.1 inhibitor of myostatin
- Binds to it
Full Body Workout
- Full body training gives a bigger reduction in myostatin compared to a split routine
- Training full body is better than just lower body or worse just the upper body (full body > lower body > upper body)
Nucleus Overload
- High frequency training
- Drop in myostatin only lasts for about 8-12 hours (This is also the reason why protein synthesis peaks within the 24-hour period)
- MGF (IGF-1) 12-24 hours post workout
Eccentric
- Heavy Negatives
- Or you can do high volume concentrics to match heavy negative, It’s one or the other
Anabolic Hormones
- Any anabolic hormones will lower myostatin
- Testosterone
- IGF-1
- MGF (Mechano Growth Factor)
- Growth hormone
Lactic Acid
- Lactic acid lead to a lower myostatin
- Increases Follistatin
High Protein Diet
- Especially Leucine
- Amino acids
Caffeine
- Improves Follistatin to Myostatin ratio
Creatine
- Lowers myostatin
Epicathenin
- Is shown to lower myostatin
- In green tea
- In dark chocolate